Pat Sadat-Ngatchou

Current Lab Project

My main project in the Herzenberb lab involves understanding mechanisms that regulate B-1 lymphocytes repertoires. I am especially interested in the role that IL-7 plays in modulating the generation of B-1 cells expressing VH11 natural antibodies.

I am also currently examining the effects of HIV tat on murine lymphocytes in vitro.

In addition, I am collaborating with Yael Gernez  MD to determine biomarkers of human basophils in food allergies.

 Past Publications

 Sadate-Ngatchou PI, Payne CJ, Dearth AT, Braun RE. “Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice.” Genesis. 2008 Dec;46(12):738-42.

 Sadate-Ngatchou PI, Pouchnik DJ, Griswold MD. “Follicle-stimulating hormone induced changes in gene expression of murine testis.” Mol Endocrinol. 2004 Nov;18(11):2805-16. Epub 2004 Aug 5.

 Sadate-Ngatchou PI, Pouchnik DJ, Griswold MD. “Identification of testosterone-regulated genes in testes of hypogonadal mice using oligonucleotide microarray.” Mol Endocrinol. 2004 Feb;18(2):422-33. Epub 2003 Nov 6.